Sodium valproate and other AED's
Epilepsy has an impact on the reproductive system. Males with epilepsy have lower fertility rates, hyposexuality and reduced potency compared with the general population. Anti-epileptic drugs and
epilepsy itself are thought to be responsible for this.
Risks during pregnancy
It is well established that women who take antiepileptics during pregnancy have a higher risk of having a child with a birth defect than
do women in the general population—this risk is estimated to be 2 to 3 times higher. This risk is further increased if a woman takes more than one antiepileptic medicine during pregnancy.
The use of sodium valproate is associated with a greater
risk of some types of these malformations (in particular neural tube defects) than with some other antiepileptic drugs. This risk is clearly reflected in the product information provided for patients and prescribers.
Dr Henry Marsh. I find this Clinicians honesty both truthful and enlightening. Everyone needs hope. #brainsurgery for Epilepsy.
FACS Association email@example.com. uk
Pregnancy & Sodium Valproate.